Multicompartmental Poroelastic Modelling for CSF Production and Circulation

نویسندگان

  • John C. VARDAKIS
  • Brett TULLY
  • James BYRNE
  • Yiannis VENTIKOS
چکیده

This study proposes the implementation of a Multiple-Network Poroelastic Theory (MPET) model for the purpose of investigating in detail the transport of water within the cerebral environment. The advantage of using the MPET representation is that it accounts for fluid transport between CSF, brain parenchyma and cerebral blood. They key novelty in the model discussed in the present study is the amalgamation of anatomically accurate Choroid Plexus regions, with their individual feeding arteries. This model is used to demonstrate the impact of aqueductal stenosis and atresia of the Foramina of Luschka and Magendie on the cerebral ventricles. The possible implications of treating such a condition with the aid of endoscopic third ventriculostomy are investigated and discussed.

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تاریخ انتشار 2011